pentobarbital will reduce the extent or outcome of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of abemaciclib with potent CYP3A4 inducers lowers plasma concentration of abemaciclib and its metabolites.
pentobarbital will lessen the extent or outcome of nimodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital decreases effects of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of CYP3A4 inducers might reduce sufentanil ranges and efficacy, probably precipitating withdrawal syndrome in sufferers who definitely have formulated Actual physical dependence to sufentanil. Discontinuation of concomitantly employed CYP3A4 inducers may well improve sufentanil plasma concentration.
This drug may well interfere Using the absorption of orally administered griseofulvin, decreasing its blood levels; effects of blood amount reduction unknown; preferable in order to avoid concomitant administration more info of those medicines
pentobarbital will decrease the level or influence of roflumilast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not advised; solid cytochrome P450 enzyme inducers lower systemic publicity to roflumilast and may decrease the therapeutic performance
pentobarbital will decrease the extent or outcome of alfuzosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.
pentobarbital will reduce the extent or outcome of doxorubicin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will minimize the level or influence of etravirine by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the extent or effect of tipranavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will reduce the level or outcome of isavuconazonium sulfate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lessen the level or impact of indinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Contraindicated (one)pentobarbital will decrease the level or result of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with potent CYP3A4 inducers isn't advised
pentobarbital will reduce the extent or impact of nelfinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the extent or effect of solifenacin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.